The GenieFluorâ„¢ 647 Anti-Mouse CD4 Antibody (Clone: GK1.5) from Assay Genie is a highly specific and reliable tool for researchers studying CD4-positive T cells in mouse models. This monoclonal antibody is designed for use in flow cytometry, immunofluorescence, and immunohistochemistry applications, providing accurate and detailed analysis of CD4 expression patterns in different tissues and cell populations.The GK1.5 antibody recognizes the CD4 antigen, a key cell surface marker expressed on T helper cells, regulatory T cells, and other immune cell subsets. By targeting CD4, researchers can identify, quantify, and characterize these important immune cell populations in experimental settings, enhancing our understanding of immune responses, immune-mediated diseases, and therapeutic interventions.
With its exceptional specificity and sensitivity, the GenieFluorâ„¢ 647 Anti-Mouse CD4 Antibody offers a valuable tool for immunologists, cancer biologists, and researchers investigating infectious diseases and autoimmune conditions. Its reliable performance and consistent results make it an essential reagent for studies aiming to unravel the complex roles of CD4-positive T cells in health and disease.
Genie Fluor 647 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
Genie Fluor647
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P06332
Gene ID:
12504
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD4 is a 55 kD protein also known as L3T4 or T4. It is a member of the Ig superfamily, primarily expressed on most thymocytes, a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a coreceptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosin kinase, lck.