The GenieFluor 647 Anti-Mouse CD36 Antibody (HM36) is a powerful tool for researchers investigating the CD36 protein, a cell surface molecule with diverse functions in the immune system and beyond. This antibody, specifically designed for use with mouse samples, is raised in rabbits and exhibits high reactivity and specificity. Validated for use in various applications such as immunofluorescence and flow cytometry, the GenieFluor 647 Anti-Mouse CD36 Antibody (HM36) allows for precise detection and analysis of CD36 expression in different cell types.CD36, a multifaceted receptor known for its roles in lipid metabolism, inflammation, and immune response modulation, is a key player in processes like atherosclerosis, diabetes, and infectious diseases.
By targeting CD36 with this high-quality antibody, researchers can delve into its functions within these contexts and unravel its involvement in various pathologies. The ability to visualize and quantify CD36 expression in mouse samples opens up new possibilities for exploring the mechanisms underlying CD36-related diseases and developing potential therapeutic strategies.
Product Title:
GenieFluor 647 Anti-Mouse CD36 Antibody [HM36]
SKU:
AGEL3303
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
HM36
Synonyms:
FAT; gpIIIb; gpIV;
Host Species:
Armenian Hamster
Reactivity:
Mouse
Application:
FCM
Isotype:
Armenian Hamster IgG
Isotype Control:
Genie Fluor 647 Armenian Hamster IgG Isotype Control[PIP]
Form:
Liquid
Conjugation:
Genie Fluor647
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
Q08857
Gene ID:
12491Â
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD36 is a 85 kD glycoprotein, also known as FAT, gpIIIb, or gpIV. It is a member of the class B scavenger receptor family, expressed on platelets, monocytes, macrophages, megakaryocytes, microvasculature, dendritic cells and mammary endothelial cells. The primary ligands for CD36 have been reported to be oxidized low density lipoprotein, anionic phospholipids, and collagens I, IV, and V. CD36 acts as a scavenger receptor thus promoting the removal of apoptotic neutrophils and other apoptotic bodies, as well as clearance of defective erythrocytes.