null

GenieFluor 647 Anti-Mouse CD335 Antibody [29A1.4] (AGEL3333)

SKU:
AGEL3333
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, k
Clone:
29A1.4
Conjugation:
AF647
€199 - €539
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

GenieFluor 647 Anti-Mouse CD335 Antibody [29A1.4]

The GenieFluor 647 Anti-Mouse CD335 Antibody (29A1.4) is a highly specific and sensitive tool designed for research involving CD335, a cell surface receptor known as NKp46. This monoclonal antibody, raised in mice, exhibits exceptional reactivity with mouse samples and is validated for use in various immunofluorescence and flow cytometry applications. By targeting the CD335 protein, this antibody enables precise detection and analysis of NK cells expressing NKp46, facilitating in-depth studies in immunology and cancer research.CD335, also referred to as Natural Cytotoxicity Triggering Receptor 1 (NCR1), is a key player in the activation and regulation of natural killer (NK) cells, which are integral components of the innate immune system responsible for recognizing and eliminating virally infected cells and cancer cells.

Understanding the function and expression of CD335 is crucial for unraveling the mechanisms underlying NK cell-mediated cytotoxicity and immunosurveillance. Research focused on CD335 has implications for developing novel immunotherapies targeting NK cells for the treatment of infectious diseases and cancer.

Product Title:GenieFluor 647 Anti-Mouse CD335 Antibody [29A1.4]
SKU:AGEL3333
Size:25µg, 100µg
Clone No:29A1.4
Synonyms:Ly94;mAR-1;NK-p46;mNKp46;Lymphocyte antigen 94;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:Genie Fluor 647 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q8C567
Gene ID:17086
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD335, also known as NKp46, is a single-pass type I membrane protein of 46 kD. It belongs to the natural cytotoxicity receptor (NCR) family and contains two Ig-like (immunoglobulin-like) domains. It's expression is restricted to NK cells and a subset of NKT cells; it's not expressed in CD1d-restricted NKT cells. CD335 is a receptor for viral hemagglutinins and heparan sulfate proteoglycans and is involved in NK cell activation.

Related Products