The GenieFluor 647 Anti-Mouse CD335 Antibody (29A1.4) is a cutting-edge product designed for researchers studying CD335, a key cell surface receptor involved in immune function. This high-quality antibody, developed specifically for mouse samples, is ideal for a range of applications, including flow cytometry, immunofluorescence, and immunohistochemistry.CD335, also known as NKp46, is a critical marker found on natural killer (NK) cells and plays a crucial role in innate immunity and the body's defense against pathogens and tumors. By targeting CD335, researchers can gain valuable insights into NK cell activity and function, making this antibody a valuable tool for studies in immunology, cancer research, and infectious diseases.
Characterized by its high specificity and sensitivity, the GenieFluor 647 Anti-Mouse CD335 Antibody (29A1.4) enables accurate detection and analysis of CD335 expression in various mouse cell types, providing researchers with a deeper understanding of NK cell biology and immunity. With its proven performance and reliability, this antibody is a must-have for any lab conducting cutting-edge research in the field of immunology.
Product Title:
GenieFluor 647 Anti-Mouse CD335 Antibody [29A1.4]
SKU:
AGEL3332
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
29A1.4
Synonyms:
Ly94;mAR-1;NK-p46;mNKp46;Lymphocyte antigen 94;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
Genie Fluor 647 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
Genie Fluor647
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
Q8C567
Gene ID:
17086
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD335, also known as NKp46, is a single-pass type I membrane protein of 46 kD. It belongs to the natural cytotoxicity receptor (NCR) family and contains two Ig-like (immunoglobulin-like) domains. It's expression is restricted to NK cells and a subset of NKT cells; it's not expressed in CD1d-restricted NKT cells. CD335 is a receptor for viral hemagglutinins and heparan sulfate proteoglycans and is involved in NK cell activation.