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GenieFluor 647 Anti-Mouse CD163 Antibody [S15049F] (AGEL3396)

SKU:
AGEL3396
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, k
Clone:
S15049F
Conjugation:
AF647
€259 - €609
Frequently bought together:

Description

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GenieFluor 647 Anti-Mouse CD163 Antibody [S15049F]

The GenieFluor 647 Anti-Mouse CD163 Antibody (S15049F-AGEL3396) offered by AssayGenie is a powerful tool for researchers studying CD163, a cell surface marker known for its role in macrophage biology and its involvement in various pathological processes. This antibody is specifically designed for use in mouse samples, enabling researchers to detect and analyze CD163 expression with high specificity and sensitivity.CD163 is a scavenger receptor involved in the clearance of hemoglobin-haptoglobin complexes and plays a crucial role in the resolution of inflammation. Its expression is often associated with macrophage polarization and can serve as a marker for specific macrophage subsets in different tissues.

By targeting CD163 with this antibody, researchers can explore the dynamics of macrophage activation, polarization, and function in various physiological and pathological conditions.The GenieFluor 647 Anti-Mouse CD163 Antibody is highly validated for applications such as immunofluorescence and flow cytometry, providing researchers with reliable and reproducible results for their experiments. Whether studying macrophage biology, inflammation, or diseases related to macrophage dysfunction, this antibody is a valuable tool for understanding the intricate role of CD163 in immune responses and tissue homeostasis.

Product Title:GenieFluor 647 Anti-Mouse CD163 Antibody [S15049F]
SKU:AGEL3396
Size:50 Tests, 100 Tests, 200 Tests
Clone No:S15049F
Synonyms:M130; MM130; SCARI1;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:Genie Fluor 647 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q2VLH6
Gene ID:93671
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD163 is a member of the group B scavenger receptor cysteine-rich superfamily, also known as GHI/61, M130, RM3/1, p155, hemoglobin-haptoglobin complex receptor, or macrophage-associated antigen. It is a 134 kD (non-reduced)/155 kD (reduced) glycoprotein primarily expressed on macrophages, Kupffer cells, monocytes, a subset of dendritic cells, and a subset of hematopoietic stem/progenitor cells. CD163 binds to haptoglobin-hemoglobin complex and TWEAK, and plays a role in clearing hemoglobin and regulating cytokine production by macrophages. Membrane CD163 can be cleaved by metalloproteinases (MMP), resulting in a soluble form. Elevated serum level of sCD163 has been implicated in many kinds of inflammatory diseases.

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