The GenieFluor 647 Anti-Mouse CD117 Antibody (2B8) is a highly specific and reliable tool for researchers studying CD117, a cell surface receptor commonly known as c-kit. This antibody, engineered for use in mouse samples, is produced and validated by Assay Genie to ensure high performance in various experimental techniques such as flow cytometry, immunofluorescence, and immunohistochemistry.CD117, a crucial marker for hematopoietic stem cells and mast cells, is involved in essential cellular processes such as cell survival, proliferation, and differentiation. The GenieFluor 647 Anti-Mouse CD117 Antibody (2B8) specifically targets the CD117 protein, enabling precise detection and visualization of this important receptor in different cell types and tissues.
Its versatility and sensitivity make it an invaluable tool for investigating cell biology, immunology, and cancer research.Researchers focusing on hematopoiesis, mast cell biology, and related fields will benefit from the high quality and performance of the GenieFluor 647 Anti-Mouse CD117 Antibody (2B8). With its ability to accurately detect CD117 expression in mouse samples, this antibody facilitates detailed analysis and understanding of the complex mechanisms involving this key receptor. Unlock new insights and advance your research with the GenieFluor 647 Anti-Mouse CD117 Antibody (2B8) from Assay Genie.
Genie Fluor 647 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
Genie Fluor647
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P05532
Gene ID:
16590
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD117 is a 145 kD immunoglobulin superfamily member also known as c-Kit and stem cell factor receptor (SCFR). It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor). CD117 is expressed on hematopoietic stem cells (including multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid lineages, and T and B cell precursors), mast cells, and acute myeloid leukemia (AML) cells. CD117 interaction with its ligand is critical for the development of hematopoietic stem cells.