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GenieFluor 647 Anti-Mouse CD107a Antibody [1D4B] (AGEL3294)

SKU:
AGEL3294
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
ICFCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, k
Clone:
1D4B
Conjugation:
AF647
$311 - $731
Frequently bought together:

Description

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GenieFluor 647 Anti-Mouse CD107a Antibody [1D4B]

The GenieFluor 647 Anti-Mouse CD107a Antibody (1D4B) offered by AssayGenie is a potent tool for research involving CD107a, a marker protein used to detect degranulation in mouse cells. This high-quality antibody is specifically designed for use in flow cytometry and immunofluorescence applications. With its strong reactivity towards mouse samples, researchers can rely on its accuracy and sensitivity for detecting CD107a expression levels and studying cell degranulation processes in various experimental settings.CD107a, also known as lysosomal-associated membrane protein 1 (LAMP-1), is an essential component of cytotoxic granules and is commonly used as a marker for cytotoxic T lymphocytes and natural killer cells.

The degranulation process mediated by CD107a is crucial for the immune response against infected or malignant cells. By targeting CD107a with this antibody, researchers can gain valuable insights into the mechanisms underlying immune surveillance and cytotoxicity, with potential implications for cancer immunotherapy and infectious disease research.Enhance your studies in immunology, oncology, and cellular biology with the GenieFluor 647 Anti-Mouse CD107a Antibody (1D4B) from AssayGenie. Trust in its performance and specificity to advance your research and uncover new discoveries in the field of cellular immunology.

Product Title:GenieFluor 647 Anti-Mouse CD107a Antibody [1D4B]
SKU:AGEL3294
Size:50 Tests, 100 Tests, 200 Tests
Clone No:1D4B
Synonyms:LAMP-1;Lysosome-associated membrane glycoprotein 1; lysosomal membrane glycoprotein 1; CD107 antigen-like family member A; lysosome-associated membrane protein 1;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:Genie Fluor 647 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P11438
Gene ID:16783
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:The 1D4B antibody recognizes CD107a which is also known as, Lysosome-Associated Membrane Protein 1 (LAMP-1). CD107a is one of the two major glycoproteins in lysosome membranes that provide useful markers to distinguish lysosomes from other organelles. CD107a may play a role in the lysosomal degradation of certain molecules. Mouse CD107a is a type I transmembrane glycoprotein. It consists of a 40-kDa core protein which is heavily glycosylated to form heterogeneous mature glycoprotein of 110-140 kDa. It is principally expressed in epithelial cells and macrophages in a variety of organs. Following activation, CD107a is relocated to the surface of some lymphocytes, macrophages, epithelial cells, endothelial cells, platelets, and tumor cells. Cell-surface CD107a may participate in intercellular adhesion and adhesion to the extracellular matrix. Cell surface CD107a expression can serve as a useful marker for cytotoxic NK and CD8+ T cells, as well as, some malignant tumor cells.

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