The GenieFluor 647 Anti-Human MPO Antibody (ABT-101007) is a specialized tool for researchers studying myeloperoxidase (MPO), an enzyme involved in the immune response and inflammatory processes. This antibody is designed for use in various applications, including immunofluorescence and flow cytometry, allowing for the specific detection and analysis of human MPO in different cell types.MPO is a key enzyme released by neutrophils and plays a crucial role in the immune system's defense against pathogens. Dysregulation of MPO activity has been implicated in various inflammatory conditions, cardiovascular diseases, and cancer.
By targeting human MPO with high specificity, this antibody provides researchers with a valuable tool to investigate the role of MPO in these diseases and develop new therapeutic strategies.The GenieFluor 647 Anti-Human MPO Antibody (ABT-101007) offers excellent sensitivity and reproducibility in detecting MPO, making it an essential reagent for studies focused on understanding the function and regulation of this important enzyme in both normal and pathological conditions. Its reliability and specificity ensure accurate results, making it a go-to choice for immunology and disease research.
Product Name:
AF647 Anti-Human MPO Antibody [ABT-101007]
Product Code:
AGEL3503
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
ABT-101007
Synonyms:
Myeloperoxidase
Reactivity:
Human
Host Species:
Mouse
Applications:
ICFCM
Isotype:
Mouse IgG1, κ
Isotype Control:
AF647 Mouse IgG1, κ Isotype Control [MOPC-21]
Conjugation:
AF647
Applications:
ICFCM
Recommended Dilution:
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage:
Keep as concentrated solution. Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Fluorescent Label:
GenieFluor 647 is designed to be excited by the Red laser (627-640 nm) and detected using an optical filter centered near 670 nm (e.g., a 660/20 nm bandpass filter).
Shipping:
Biological ice pack at 4°C
Form:
Liquid
Gene ID:
4353
Swissprot:
P05164
Background Information:
Myeloperoxidase (MPO) is a heterotetrameric protein consisting of two 60 kD heavy units and two 12 kD light units. A lysosomal enzyme, MPO is able to catalyze the production of hypochlorous acid, a potent microbicidal agent, from hydrogen peroxide and chloride anion during the neutrophil respiratory burst. MPO is a major enzyme involved in the inflammatory responses of polymorphonuclear leucocytes. MPO is localized to the azurophilic granules of mature granulocytes and monocytes and is also expressed in some acute myeloid leukemia cells.