The GenieFluor 647 Anti-Human IL-10 Antibody (JES3-9D7) from Assay Genie is a cutting-edge tool designed for studying the role of interleukin-10 (IL-10) in immune response regulation. With its specificity towards human IL-10, this antibody is essential for researchers investigating the functions of this key cytokine in various biological processes.IL-10 is a potent anti-inflammatory cytokine that plays a crucial role in modulating immune responses and maintaining immune homeostasis. It is involved in suppressing excessive inflammation and immune reactions, making it a promising target for research in fields such as immunology, autoimmunity, and infectious diseases.The GenieFluor 647 Anti-Human IL-10 Antibody (JES3-9D7) offers high specificity and sensitivity in detecting and quantifying IL-10 levels in biological samples.
Its exceptional performance in techniques like flow cytometry, immunofluorescence, and immunohistochemistry makes it a versatile tool for investigating the expression and localization of IL-10 in different cell types and tissues.Researchers can rely on this antibody to gain insights into the complex interplay of IL-10 in immune regulation, inflammation, and disease pathogenesis. By utilizing the GenieFluor 647 Anti-Human IL-10 Antibody (JES3-9D7), scientists can advance their understanding of IL-10 biology and potentially uncover new therapeutic strategies for manipulating immune responses effectively.
Genie Fluor 647 Rat IgG1, κ Isotype Control[HRPN]
Form:
Liquid
Conjugation:
Genie Fluor647
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P22301
Gene ID:
3586
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
IL-10 was originally described as Cytokine Synthesis Inhibitory Factor (CSIF) by virtue of its ability to inhibit cytokine production by Th1 clones. IL-10 shares over 80% sequence homology with the Epstein-Barr virus protein BCRFI. The biological activities of IL-10 include inhibition of macrophage-mediated cytokine synthesis, suppression of the delayed type hypersensitivity response, and stimulation of the Th2 cell response, which results in elevated antibody production.