The GenieFluorâ„¢ 647 Anti-Human CD56 Antibody (B-A19) available on assaygenie.com is a cutting-edge research tool designed for the detection and analysis of CD56, a marker predominantly expressed on natural killer cells and a subset of T cells. This antibody, optimized for human samples, is conjugated with the GenieFluorâ„¢ 647 fluorophore, offering exceptional sensitivity and specificity in various immunofluorescence applications.CD56, also known as neural cell adhesion molecule (NCAM), plays a pivotal role in mediating cell-cell interactions and is crucial for the function of immune cells. The GenieFluorâ„¢ 647 Anti-Human CD56 Antibody (B-A19) enables researchers to visualize and quantify CD56 expression in different cell populations, making it an invaluable tool for studies in immunology, neuroscience, and cancer research.
By accurately detecting CD56 expression, researchers can gain insights into immune cell function, neural development, and the role of CD56 in various disease states. The GenieFluorâ„¢ 647 Anti-Human CD56 Antibody (B-A19) is a reliable reagent for researchers seeking to explore the intricate mechanisms involving CD56 and its implications in health and disease.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P51677
Gene ID:
4684
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD56 is a single transmembrane glycoprotein also known as NCAM (neural cell adhesion molecule), Leu-19, or NKH1. It is a member of the Ig superfamily. The 140 kD isoform is expressed on NK and NKT cells. CD56 is also expressed in the brain (cerebellum and cortex) and at neuromuscular junctions. Certain large granular lymphocyte (LGL) leukemias, small-cell lung carcinomas, neuronal derived tumors, myelomas, and myeloid leukemias also express CD56. CD56 plays a role in homophilic and heterophilic adhesion via binding to itself or heparan sulfate.