The GenieFluor 647 Anti-Human CD39 Antibody (A1) offered by Assay Genie is a cutting-edge tool for research involving CD39, an integral cell surface molecule with key roles in immune regulation and modulating immune responses. This antibody is specifically developed and validated for use with human samples, ensuring accurate and reliable results in a variety of experimental settings.The GenieFluor 647 Anti-Human CD39 Antibody (A1) is a potent research tool for investigating the functions and mechanisms of CD39 in immunology, inflammation, and related pathways. Its high specificity and sensitivity allow for precise detection and analysis of CD39 protein expression in different cell types, offering valuable insights into its involvement in various physiological and pathological processes.
By targeting CD39, researchers can explore its implications in diseases such as cancer, autoimmune disorders, and inflammatory conditions. Understanding the intricate role of CD39 in immune regulation is crucial for developing targeted therapies and interventions that can modulate immune responses effectively.Overall, the GenieFluor 647 Anti-Human CD39 Antibody (A1) from Assay Genie is a versatile and reliable tool that empowers researchers to delve deeper into the intricate workings of the immune system and its implications in health and disease.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P49961
Gene ID:
953
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
Human CD39 is an integral membrane protein with two transmembrane domains. It exists as a homotetramer. Expression of CD39 is found on activated lymphocytes, a subset of T cells and B cells, and dendritic cells with weak staining on monocytes and granulocytes. CD39 and CD73 have been found on regulatory T cells, specifically the effector/memory like T cells. CD39 can hydrolyze both nucleoside triphosphates and diphosphates. CD39 is the dominant ecto nucleotidase of vascular and placental trophoblastic tissues and appears to modulate the functional expression of type 2 purinergic (P2) G protein coupled receptors (GPCRs). CD39 has intrinsic ecto-ATPase activity. Expression of CD39 is induced on T cells and increased on B cells as a late activation antigen. Product Details