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GenieFluor 647 Anti-Human CD161 Antibody [HP-3G10] (AGEL2285)

SKU:
AGEL2285
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG1, κ
Clone:
HP-3G10
Conjugation:
AF647
€269 - €889
Frequently bought together:

Description

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GenieFluor 647 Anti-Human CD161 Antibody [HP-3G10]

The GenieFluor 647 Anti-Human CD161 Antibody (HP-3G10) available at www.assaygenie.com is a specialized tool for researchers interested in the CD161 cell surface molecule. CD161, also known as NKR-P1A, is a receptor expressed on natural killer cells and other T cell subsets, playing a role in immune function and regulation.This high-quality antibody is specifically designed for use in various immunological research applications, including flow cytometry and immunofluorescence. With a strong reactivity towards human samples, the GenieFluor 647 Anti-Human CD161 Antibody (HP-3G10) provides reliable and accurate detection of CD161 protein expression in different cell types.

By targeting the CD161 receptor, researchers can investigate its involvement in immune responses, cell signaling pathways, and potential implications in diseases such as autoimmune disorders or infectious diseases. The precise binding of this antibody to CD161 enables detailed analysis and exploration of CD161 functions, making it a valuable tool for studies in immunology, cellular biology, and therapeutic development.Enhance your research capabilities and deepen your understanding of CD161 biology with the GenieFluor 647 Anti-Human CD161 Antibody (HP-3G10) from Assay Genie.

Product Title:GenieFluor 647 Anti-Human CD161 Antibody [HP-3G10]
SKU:AGEL2285
Size:20 Tests, 100 Tests, 200 Tests
Clone No:HP-3G10
Synonyms:CLEC5B; NKRP1A;NKR-P1A;HNKR-P1a;KLRB1;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Genie Fluor 647 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q12918
Gene ID:3820
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD161 is a type II transmembrane glycoprotein, also known as NKR-P1A, that is expressed as a 40-44 kD homodimer. It is a member of the C-type lectin superfamily. CD161 is expressed on a majority of NK cells, NKT cells, and subsets of peripheral T cells and CD3+ thymocytes. It has been reported that Th17 cells are a subpopulation of CD4+CD161+CCR6+ cells. While the biological function of CD161 is not clear, it has been suggested to serve either as a stimulatory receptor or to inhibit NK cell-mediated cytotoxicity and cytokine production. LLT-1 (lectin-like transcript-1, also named as osteoclast inhibitory lectin or CLEC2D) is the ligand of CD161.

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