null

GenieFluor 647 Anti-Human CD16 Antibody [3G8] (AGEL2772)

SKU:
AGEL2772
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG1, κ
Clone:
3G8
Conjugation:
AF647
€219 - €699
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

GenieFluor 647 Anti-Human CD16 Antibody [3G8]

The GenieFluor 647 Anti-Human CD16 Antibody (3G8) from AssayGenie is a cutting-edge tool designed for precise and reliable detection of CD16, a crucial cell surface receptor involved in immune responses. This antibody, meticulously crafted for exceptional specificity and sensitivity, is ideal for research applications in immunology, oncology, and beyond.CD16, also known as Fc gamma receptor III (FcγRIII), plays a pivotal role in immune cell activation and antibody-dependent cellular cytotoxicity (ADCC). As a key mediator of immune function, understanding the expression and activity of CD16 is essential in unraveling its implications in various diseases, including cancer, infectious diseases, and autoimmune disorders.

The GenieFluor 647 Anti-Human CD16 Antibody (3G8) offers unparalleled performance in detecting CD16 expression in human samples, enabling researchers to delve into the intricate mechanisms of immune response modulation. Its versatility in applications such as flow cytometry, immunofluorescence, and immunohistochemistry makes it a valuable asset for studies aiming to elucidate the roles of CD16 in health and disease.Harness the power of precision and reliability with the GenieFluor 647 Anti-Human CD16 Antibody (3G8) from AssayGenie and unlock new possibilities in immunological research.

Product Title:GenieFluor 647 Anti-Human CD16 Antibody [3G8]
SKU:AGEL2772
Size:20 Tests, 100 Tests, 200 Tests
Clone No:3G8
Synonyms:FcγRIII;Fc gamma receptor;Fc gamma receptor 3;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Genie Fluor 647 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P08637 O75015
Gene ID:941
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD16 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD16 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD16 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD16 appears to be expressed later in the immune response than CD86. CD16 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Related Products