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GenieFluor 488 Anti-Mouse Perforin Antibody [S16009A] (AGEL3311)

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SKU:
AGEL3311
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
ICFCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, k
Clone:
S16009A
Conjugation:
AF488
$371 - $851

Description

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GenieFluor 488 Anti-Mouse Perforin Antibody [S16009A]

The GenieFluor 488 Anti-Mouse Perforin Antibody (S16009A-AGEL3311) is a powerful tool for researchers studying immune responses and cytotoxic T lymphocyte (CTL) activity in mice. Perforin is a key protein involved in the immune response, particularly in the context of killing target cells. This antibody, specifically designed for use in mouse samples, is raised against perforin and conjugated with the highly fluorescent GenieFluor 488 dye.By targeting perforin, this antibody allows for the visualization and quantification of perforin-positive cells in various tissues and cell types. It can be used in a range of applications, including flow cytometry, immunofluorescence microscopy, and immunohistochemistry, to investigate perforin expression and localization.

Understanding the role of perforin in immune responses is essential for advancing research in immunology, infectious diseases, and cancer immunotherapy. The GenieFluor 488 Anti-Mouse Perforin Antibody provides researchers with a reliable tool to study the mechanisms of cytotoxic T cell-mediated killing and immune surveillance in mouse models. Its high specificity and sensitivity make it an invaluable asset for studies aiming to unravel the complexities of immune defense mechanisms.

Product Title:GenieFluor 488 Anti-Mouse Perforin Antibody [S16009A]
SKU:AGEL3311
Size:25µg, 100µg
Clone No:S16009A
Synonyms:Prf1; Pfp; Pfn; Pfn-1;Cytolysin;Lymphocyte pore-forming protein;
Host Species:Rat
Reactivity:Mouse
Application:ICFCM
Isotype:Rat IgG2a, κ
Isotype Control:Genie Fluor 488 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P10820
Gene ID:18646 
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:Perforin is a 70 kD cytolytic protein that is expressed in the cytoplasmic granules of cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells. Perforin is one of the major effector molecules used by cytotoxic T cells and NK cells to mediate targeted cell lysis.

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