The GenieFluor 488 Anti-Mouse LY-6G/LY-6C (GR-1) Antibody (RB6-8C5) offered by Assay Genie is a highly specific and sensitive tool for detecting LY-6G/LY-6C surface markers in mouse samples. This antibody, generated against LY-6G/LY-6C antigens, is ideal for immunohistochemistry, flow cytometry, and other experimental techniques targeting these markers. LY-6G/LY-6C, also known as Gr-1, is commonly used to identify granulocytic cells, particularly neutrophils, in murine immune studies.
The GenieFluor 488 Anti-Mouse LY-6G/LY-6C (GR-1) Antibody (RB6-8C5) enables researchers to accurately visualize and quantify these crucial cell populations, facilitating deeper insights into immune responses, inflammation, and infectious diseases in mouse models.
Genie Fluor 488 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
Genie Fluor488
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P35461 P0CW03
Gene ID:
546644 ,17067
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
Gr-1 is a 21-25 kD protein also known as Ly-6G/Ly-6C. This myeloid differentiation antigen is a glycosylphosphatidylinositol (GPI)-linked protein expressed on granulocytes and macrophages. In bone marrow, the expression levels of Gr-1 directly correlate with granulocyte differentiation and maturation; Gr-1 is also transiently expressed on bone marrow cells in the monocyte lineage. Immature Myeloid Gr-1+ cells play a role in the development of antitumor immunity.