The GenieFluor 488 Anti-Mouse H-2 Antibody (M1/42) (AGEL2424) offered by AssayGenie is a premium product specifically designed for use in immunology research. This high-quality antibody is optimized for detecting and analyzing the H-2 cell surface molecule in mouse samples. Raised against mouse H-2 antigens, this antibody is highly reactive and provides reliable and consistent results in various experimental applications.The H-2 antigen, also known as mouse major histocompatibility complex (MHC), plays a crucial role in immune recognition and response. Understanding its expression and function is fundamental for studying immune system regulation, antigen presentation, and immune cell interactions.
The GenieFluor 488 Anti-Mouse H-2 Antibody (M1/42) (AGEL2424) enables precise detection and visualization of H-2 antigens in different cell types, making it an essential tool for investigating immune responses in research areas such as immunology, infectious diseases, and transplantation biology.With its superior specificity and sensitivity, this antibody is validated for a wide range of applications, including flow cytometry, immunofluorescence, and immunohistochemistry. Researchers can rely on the GenieFluor 488 Anti-Mouse H-2 Antibody (M1/42) (AGEL2424) to enhance their studies and gain valuable insights into the complex mechanisms of the immune system.
Product Title:
GenieFluor 488 Anti-Mouse H-2 Antibody [M1/42]
SKU:
AGEL2424
Size:
25µg, 100µg
Clone No:
M1/42
Synonyms:
Mouse major histocompatibility complex (MHC) H-2; MHC I;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
Genie Fluor 488 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
Genie Fluor488
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Gene ID:
111364
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
The M1/42 antibody reacts with the H-2 MHC class I alloantigens expressed on nucleated cells from mice of the a, b, d, j, k, s, and u haplotypes (Stallcup, KC et al, 1981). MHC class I is involved in antigen presentation to T cells expressing CD3/TCR and CD8 proteins.