The GenieFluor 488 Anti-Mouse H-2 Antibody (M1/42) is a high-quality antibody designed for researchers studying mouse immune responses and histocompatibility. This antibody, conjugated with GenieFluor 488, provides excellent sensitivity and specificity for detecting the H-2 antigen in mouse samples. Its reactivity with mouse samples has been extensively validated, making it a reliable tool for various immunological research applications.The H-2 antigen, a complex of proteins involved in antigen presentation and immune response regulation in mice, plays a crucial role in immune recognition and modulation. The GenieFluor 488 Anti-Mouse H-2 Antibody specifically targets the H-2 antigen, allowing for precise detection and analysis of H-2 expression in different cell types and tissues.
This makes it an essential reagent for studies focusing on immunology, transplantation, and immune system function in mouse models.Researchers investigating immune responses, transplantation outcomes, and immune-related diseases such as autoimmunity and infectious diseases can benefit from the accurate and reliable performance of the GenieFluor 488 Anti-Mouse H-2 Antibody. With its superior quality and specificity, this antibody provides valuable insights into the molecular mechanisms underlying immune recognition and regulation in mouse models, advancing our understanding of immune system dynamics and immune-related pathologies.
Product Title:
GenieFluor 488 Anti-Mouse H-2 Antibody [M1/42]
SKU:
AGEL2416
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
M1/42
Synonyms:
Mouse major histocompatibility complex (MHC) H-2; MHC I;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
Genie Fluor 488 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
Genie Fluor488
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Gene ID:
111364
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
The M1/42 antibody reacts with the H-2 MHC class I alloantigens expressed on nucleated cells from mice of the a, b, d, j, k, s, and u haplotypes (Stallcup, KC et al, 1981). MHC class I is involved in antigen presentation to T cells expressing CD3/TCR and CD8 proteins.