The GenieFluor 488 Anti-Mouse CD90.2 Antibody (30-H12) offered by AssayGenie is a powerful tool for researchers studying mouse CD90.2, a cell surface marker commonly used to identify mouse T cells and hematopoietic stem cells. This antibody is specifically designed to bind to CD90.2, enabling precise detection and analysis in a variety of experimental settings.Raised against mouse samples, the GenieFluor 488 Anti-Mouse CD90.2 Antibody (30-H12) is highly reactive and has been validated for use in immunofluorescence applications, making it an ideal choice for fluorescence microscopy and flow cytometry experiments. By targeting CD90.
2, this antibody facilitates the visualization and characterization of T cells and stem cells in research related to immunology, stem cell biology, and cancer immunotherapy.The expression of CD90.2 is crucial for understanding the functions and behaviors of specific immune cell populations in various physiological and pathological conditions. Researchers can leverage the GenieFluor 488 Anti-Mouse CD90.2 Antibody (30-H12) to explore the roles of CD90.2-positive cells in immune responses, stem cell differentiation, and disease progression, ultimately advancing our knowledge in these areas of study.
Genie Fluor 488 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
Genie Fluor488
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Gene ID:
21838
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD90.2 is a 25-35 kD immunoglobulin superfamily member also known as Thy1.2. It is expressed on hematopoietic stem cells and neurons, all thymocytes, and peripheral T cells in Thy1.2 bearing mouse strains (Balb/c, CBA/J, C3H/He, C57BL/-, DBA, NZB/-). CD90.2 is a glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein involved in signal transduction. CD90.2 is involved in costimulation of lymphocyte proliferation and induction of hematopoietic stem cells differentiation. CD90.2 has been shown to interact with CD45. The 30H12 antibody has been reported to induce Ca2+ flux in thymocytes and, in combination with antibody against the CD3/TCR complex, promote thymocyte apoptosis and inhibit CD3-mediated proliferative responses of mature T lymphocytes.