The GenieFluor 488 Anti-Mouse CD18 Antibody (M18/2) is a cutting-edge tool designed for researchers working in the field of immunology and cell biology. This antibody, targeted specifically against mouse CD18, is highly reactive and offers exceptional sensitivity and specificity in detecting the CD18 protein in various cell types.CD18, also known as integrin beta-2, is a crucial cell surface molecule involved in immune cell adhesion and migration. By targeting CD18, researchers can investigate cell-cell interactions, inflammatory responses, and immune cell recruitment processes. The GenieFluor 488 Anti-Mouse CD18 Antibody (M18/2) opens up exciting possibilities for studying immune cell behavior and function, making it a valuable tool for research projects focused on immunology, inflammation, and infectious diseases.
Validated for use in a variety of applications, including immunofluorescence and flow cytometry, this antibody provides researchers with a powerful tool to gain insights into the role of CD18 in health and disease. Whether exploring immune responses, characterizing immune cell populations, or studying inflammation mechanisms, the GenieFluor 488 Anti-Mouse CD18 Antibody (M18/2) offers high performance and reliability to support your research needs.
Genie Fluor 488 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
Genie Fluor488
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P11835
Gene ID:
16414
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD18 is a 95 kD protein, also known as integrin β2 subunit. It is expressed on all leukocytes. CD18, in association with integrin α chain CD11a, CD11b, and CD11c forms LFA-1, Mac-1, and αXβ2, respectively, and plays an important role in leukocytes adhesion. The CD18 integrin complexes bind ICAM-1 (CD54), ICAM-2 (CD102), ICAM-3 (CD50), iC3b, and fibrinogen.