The GenieFluor 488 Anti-Human IL-10 Antibody (JES3-9D7) is a cutting-edge tool for researchers investigating the immune system's response to interleukin-10 (IL-10), a key cytokine involved in regulating immune responses. This high-quality antibody, produced with advanced technology, specifically targets human IL-10 and is well-suited for various experimental applications.IL-10 is a vital immunoregulatory cytokine that plays a pivotal role in controlling inflammation and maintaining immune balance. Dysregulation of IL-10 is associated with numerous diseases, including autoimmune disorders, infectious diseases, and inflammatory conditions. By using the GenieFluor 488 Anti-Human IL-10 Antibody (JES3-9D7), researchers can accurately detect and analyze IL-10 levels in different cell types, shedding light on its functions and potential therapeutic implications.
This antibody offers exceptional specificity and sensitivity, allowing for precise detection of IL-10 even at low concentrations. Whether investigating the impact of IL-10 in immune modulation, studying its role in disease pathogenesis, or developing novel therapeutic interventions, the GenieFluor 488 Anti-Human IL-10 Antibody (JES3-9D7) is a valuable asset for researchers seeking to deepen their understanding of immune regulation and cytokine signaling pathways.
Genie Fluor 488 Rat IgG1, κ Isotype Control[HRPN]
Form:
Liquid
Conjugation:
Genie Fluor488
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P22301
Gene ID:
3586
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
IL-10 was originally described as Cytokine Synthesis Inhibitory Factor (CSIF) by virtue of its ability to inhibit cytokine production by Th1 clones. IL-10 shares over 80% sequence homology with the Epstein-Barr virus protein BCRFI. The biological activities of IL-10 include inhibition of macrophage-mediated cytokine synthesis, suppression of the delayed type hypersensitivity response, and stimulation of the Th2 cell response, which results in elevated antibody production.