The GenieFluorâ„¢ 488 Anti-Human IgD Antibody (IA6-2) is a cutting-edge tool for researchers delving into the complexities of the human immune system. This highly specific monoclonal antibody targets the IgD protein, a key player in the humoral immune response. It has been meticulously developed and tested for its binding affinity to human IgD, ensuring reliable and reproducible results in various experimental settings.With its fluorescent label, GenieFluorâ„¢ 488 enables precise visualization and localization of IgD in a range of biological samples. Whether used in flow cytometry, immunofluorescence microscopy, or other analytical techniques, this antibody provides researchers with a powerful tool to explore the distribution and expression of IgD in immune cells and tissues.
The study of IgD is pivotal in understanding the intricacies of humoral immunity and its role in health and disease. By utilizing the GenieFluorâ„¢ 488 Anti-Human IgD Antibody (IA6-2), researchers can unravel the functions of IgD in immune responses, antibody production, and immunological disorders. This antibody opens up new avenues for discoveries in immunology, paving the way for innovative research in fields such as immunotherapy, autoimmune diseases, and infectious diseases.
Product Title:
GenieFluor 488 Anti-Human IgD Antibody [IA6-2]
SKU:
AGEL2296
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
IA6-2
Synonyms:
Immunoglobulin heavy constant delta;IGHD;Ig delta chain C region;
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P01880
Gene ID:
3495
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
IgD, a member of the immunoglobulin (Ig) family, is expressed in naïve B cells. It has 3 Ig-like domains and exists in a transmembrane and a soluble form. In general, IgD is not secreted and usually its expression is lost after the Ig isotype switch. After antigen binding, IgD signals through the CD79a/CD79b (Igα/Igβ) heterodimer, resulting in the activation of the B cell.