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GenieFluor 488 Anti-Human CD8a Antibody [HIT8a] (AGEL3393)

SKU:
AGEL3393
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG1, k
Clone:
HIT8a
Conjugation:
AF488
€199 - €629
Frequently bought together:

Description

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GenieFluor 488 Anti-Human CD8a Antibody [HIT8a]

The GenieFluorâ„¢ 488 Anti-Human CD8a Antibody (HIT8a) offered by AssayGenie is a cutting-edge tool for immunological research. Specifically designed for the detection of the CD8a cell surface molecule, this antibody is a crucial component for analyzing immune responses in humans.CD8a is a key marker for cytotoxic T cells, playing a pivotal role in immune surveillance and response. The GenieFluorâ„¢ 488 Anti-Human CD8a Antibody enables precise and accurate detection of CD8a protein in various cell types, making it an essential tool for immunology and cancer research studies.This highly reactive antibody is rigorously validated for use in applications such as immunofluorescence and flow cytometry, providing researchers with reliable and reproducible results.

By targeting the CD8a protein, researchers can delve deeper into the mechanisms of immune response modulation, paving the way for advancements in therapies for conditions such as cancer, autoimmune disorders, and infectious diseases.Unlock the potential of your research with the GenieFluorâ„¢ 488 Anti-Human CD8a Antibody from AssayGenie. Trust in its quality and specificity to drive your investigations further into the fascinating world of immunology.

Product Title:GenieFluor 488 Anti-Human CD8a Antibody [HIT8a]
SKU:AGEL3393
Size:20 Tests, 100 Tests, 200 Tests
Clone No:HIT8a
Synonyms:T-cell surface glycoprotein CD8 alpha chain;CD8A;T8;Leu2;MAL;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Genie Fluor 488 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P01732
Gene ID:925
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.

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