The GenieFluor 488 Anti-Human CD81 Antibody (1.3.3.22) offered by AssayGenie is a powerful tool for researchers studying CD81, a key protein involved in cell adhesion and signaling processes. This antibody, optimized for detecting human CD81 samples, is ideal for use in flow cytometry, immunofluorescence, and other antibody-based assays.CD81 is a widely expressed protein found on the surface of various cell types, including B cells, T cells, and epithelial cells. It plays a crucial role in facilitating cellular interactions, such as cell adhesion, fusion, and migration. Furthermore, CD81 is involved in diverse biological processes, including immune response modulation and viral entry.The GenieFluor 488 Anti-Human CD81 Antibody (1.
3.3.22) boasts high specificity and sensitivity, enabling precise detection and analysis of CD81 in different experimental settings. Its use can provide valuable insights into the function and regulation of CD81 in normal physiological processes and disease states.Researchers investigating cell biology, immunology, virology, and cancer biology will benefit from the exceptional performance of this antibody in their studies. By targeting CD81, this antibody opens up possibilities for exploring novel therapeutic strategies and understanding the molecular mechanisms underlying various pathologies. Unlock the potential of your research with the GenieFluor 488 Anti-Human CD81 Antibody (1.3.3.22) from AssayGenie.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P60033
Gene ID:
975
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD81 is a 26 kD non-glycosylated member of the tetraspanin superfamily (TM4SF), also known as TAPA-1 (target of an antiproliferative antibody). CD81 is expressed on T and B cells, NK cells, monocytes, dendritic cells, thymocytes, endothelial cells, and fibroblasts. It also has low levels of expression on granulocytes. CD81 induces B cell adhesion via VLA-4 integrin and has been shown to play a role in early T cell development. CD81 associates with several other cell-surface proteins in a multimolecular complex, including CD19, CD21, CD20, CD37, CD53, and CD82 in B cells, and CD4, CD8 and CD82 in T cells.