The GenieFluor 488 Anti-Human CD44 Antibody (P2A1) offered by Assay Genie is a cutting-edge tool for researchers investigating CD44, a key cell surface glycoprotein associated with various physiological and pathological processes. This antibody is specifically designed for use in immunofluorescence applications, providing high sensitivity and specificity in detecting CD44 expression in human samples.CD44 is a multifunctional molecule involved in cell adhesion, migration, and signaling, playing crucial roles in processes such as inflammation, tissue repair, and cancer metastasis. The GenieFluor 488 Anti-Human CD44 Antibody (P2A1) enables precise visualization and analysis of CD44 distribution and expression levels in different cell types and tissues, making it an indispensable tool for research in immunology, oncology, and regenerative medicine.
With its superior performance and reliability, this antibody offers researchers a valuable resource to deepen their understanding of CD44 biology and its implications in various disease states. By providing detailed insights into the role of CD44, this antibody facilitates the development of novel therapeutic strategies targeting CD44-related pathways, ultimately advancing the field of biomedical research.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P16070
Gene ID:
960
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from a low or mid level of intensity to high expression levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.