The GenieFluor 488 Anti-Human CD39 Antibody (A1) is a cutting-edge tool designed for researchers studying CD39, a key cell surface enzyme involved in immune regulation and the suppression of immune responses. This antibody is specifically targeted towards human samples, offering high reactivity and accuracy in experimental settings.Raised with precision in the laboratory, the GenieFluor 488 Anti-Human CD39 Antibody (A1) is ideal for a range of applications, including fluorescence microscopy, flow cytometry, and immunofluorescence assays. By binding specifically to the CD39 protein, researchers can confidently detect and analyze CD39 expression in various cell types, providing valuable insights into immune processes and disease mechanisms.CD39, a critical player in immune modulation, is known for its ability to regulate inflammation and suppress excessive immune responses.
Its involvement in maintaining immune balance makes it a compelling target for investigations into conditions such as cancer, autoimmune disorders, and inflammatory diseases. By delving into the functions of CD39, researchers can uncover new therapeutic targets and potential interventions for these complex health challenges.Whether exploring the role of CD39 in immunology, cancer biology, or other research areas, the GenieFluor 488 Anti-Human CD39 Antibody (A1) stands as a powerful and reliable tool for unraveling the mysteries of immune regulation and disease progression. Drive your research forward with confidence and precision using this advanced antibody designed to enhance your experimental outcomes and scientific discoveries.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P49961
Gene ID:
953
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
Human CD39 is an integral membrane protein with two transmembrane domains. It exists as a homotetramer. Expression of CD39 is found on activated lymphocytes, a subset of T cells and B cells, and dendritic cells with weak staining on monocytes and granulocytes. CD39 and CD73 have been found on regulatory T cells, specifically the effector/memory like T cells. CD39 can hydrolyze both nucleoside triphosphates and diphosphates. CD39 is the dominant ecto nucleotidase of vascular and placental trophoblastic tissues and appears to modulate the functional expression of type 2 purinergic (P2) G protein coupled receptors (GPCRs). CD39 has intrinsic ecto-ATPase activity. Expression of CD39 is induced on T cells and increased on B cells as a late activation antigen. Product Details