The GenieFluor 488 Anti-Human CD33 Antibody (6C5) offered by AssayGenie is a cutting-edge tool for researchers studying CD33, a cell surface glycoprotein involved in immune responses and cell adhesion. This antibody, designed for use in immunofluorescence and flow cytometry applications, is specifically engineered to target human CD33 with high specificity and sensitivity.CD33 is known to play a crucial role in the regulation of myeloid cell functions and has been implicated in various diseases, including acute myeloid leukemia (AML) and other hematological malignancies. By utilizing the GenieFluor 488 Anti-Human CD33 Antibody (6C5), researchers can effectively detect and analyze CD33 expression in different cell types, aiding in the understanding of its role in disease pathology and immunology.
This advanced antibody provides a valuable tool for investigating the function of CD33 in both normal and diseased conditions, opening up new possibilities for therapeutic interventions and targeted treatments. With its strong fluorescence signal and high specificity, the GenieFluor 488 Anti-Human CD33 Antibody (6C5) is a reliable choice for researchers seeking to unravel the complexities of CD33 biology and its implications in disease progression and treatment strategies.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P20138
Gene ID:
945
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD33 is a 67 kD type I transmembrane glycoprotein also known as Siglec-3, gp67, and p67. It is a sialoadhesion immunoglobulin superfamily member expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells and mast cells. CD33 is absent on normal platelets, lymphocytes, erythrocytes and hematopoietic stem cells. CD33 functions as a sialic acid-dependent cell adhesion molecule with carbohydrate/lectin binding activity.