The GenieFluor 488 Anti-Human CD31 Antibody (158-2B3) from Assay Genie is a highly specific antibody designed for the detection of CD31, a cell surface glycoprotein known to be a marker of endothelial cells. This antibody is conjugated with the GenieFluor 488 fluorophore, providing excellent sensitivity and signal intensity for fluorescence-based assays.CD31, also known as platelet endothelial cell adhesion molecule-1 (PECAM-1), plays a crucial role in various biological processes, including endothelial cell adhesion, migration, and angiogenesis. The anti-human CD31 antibody is validated for use in immunofluorescence, flow cytometry, and immunohistochemistry applications, allowing for precise visualization and analysis of CD31 expression in tissue samples and cell cultures.
With its high specificity and sensitivity, the GenieFluor 488 Anti-Human CD31 Antibody (158-2B3) is ideal for research in vascular biology, angiogenesis, and inflammatory disorders where CD31 expression is of interest. Researchers can rely on this antibody to accurately detect and quantify CD31 levels in various experimental settings, enabling in-depth investigation into the role of CD31 in physiological and pathological processes.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P16284
Gene ID:
5175
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD31 is a 130-140 kD type I transmembrane glycoprotein also known as platelet endothelial cell adhesion molecule-1 (PECAM-1) or Endocam. It is expressed on monocytes, platelets, granulocytes, endothelial cells and lymphocyte subsets. CD31 has been reported to bind CD38 and be involved in wound healing, angiogenesis, and cellular migration in an inflammatory situation.