The GenieFluor 488 Anti-Human CD3 Antibody (UCHT1) offered by Assay Genie is a cutting-edge tool designed for researchers studying CD3, a pivotal cell surface marker found on T cells. This high-quality antibody, optimized for human samples, is a powerful resource for immunologists and oncologists alike. With its potent binding capacity to the CD3 protein, the GenieFluor 488 Anti-Human CD3 Antibody facilitates precise detection and analysis in a variety of cell types, making it an essential component for investigations in immunology and cancer research.The CD3 complex is integral to T cell receptor signaling, playing a crucial role in orchestrating immune responses and cellular interactions.
Research involving CD3 has far-reaching implications, from understanding basic immunological mechanisms to developing innovative therapies for diseases such as cancer and autoimmune disorders. The GenieFluor 488 Anti-Human CD3 Antibody provides researchers with a reliable tool to explore the functions and dynamics of CD3 in diverse experimental settings, enabling groundbreaking discoveries in the field of immunology and beyond.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P07766
Gene ID:
915
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD3ε is a 20 kD chain of the CD3/T cell receptor (TCR) complex, which is composed of two CD3ε, one CD3γ, one CD3δ, one CD3ζ (CD247), and a T cell receptor (α/β or γ/δ) heterodimer. It is found on all mature T lymphocytes, NK T cells, and some thymocytes. CD3, also known as T3, is a member of the immunoglobulin superfamily that plays a role in antigen recognition, signal transduction, and T cell activation.