The GenieFluor 488 Anti-Human CD20 Antibody (BCA-B20) is a cutting-edge tool for research in immunology and oncology. Specifically designed to target the CD20 protein found on the surface of B cells, this antibody is a valuable asset for investigating B cell biology and related diseases.Developed with precision and rigor, the GenieFluor 488 Anti-Human CD20 Antibody (BCA-B20) boasts high specificity and sensitivity in detecting the CD20 antigen in human samples. Its fluorochrome labeling with GenieFluor 488 enables fluorescent microscopy and flow cytometry applications with exceptional clarity and resolution.
Whether you are exploring the role of CD20 in autoimmune disorders, lymphomas, or other B cell-related conditions, this antibody provides a reliable tool for your research needs. Trust in the quality and performance of the GenieFluor 488 Anti-Human CD20 Antibody (BCA-B20) to advance your studies and uncover new insights into B cell biology and disease mechanisms.
Product Title:
GenieFluor 488 Anti-Human CD20 Antibody [BCA/B20]
SKU:
AGEL2816
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
BCA/B20
Synonyms:
B-lymphocyte antigen CD20;MS4A1;B-lymphocyte surface antigen B1;Bp35;Leukocyte surface antigen Leu-16;Membrane-spanning 4-domains subfamily A member 1;MS4A1;CD20;
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P11836
Gene ID:
931
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82.