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GenieFluor 488 Anti-Human CD107a/LAMP-1 Antibody [H4A3] (AGEL3150)

SKU:
AGEL3150
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG1, κ
Clone:
H4A3
Conjugation:
AF488
$287 - $995
Frequently bought together:

Description

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GenieFluor 488 Anti-Human CD107a/LAMP-1 Antibody [H4A3]

The GenieFluor 488 Anti-Human CD107a (LAMP-1) Antibody (H4A3) offered by AssayGenie is a cutting-edge tool for researchers studying the CD107a protein, also known as Lysosomal-associated membrane protein 1 (LAMP-1). This antibody is specifically designed for use in immunofluorescence and flow cytometry applications, providing high sensitivity and specificity in detecting CD107a/LAMP-1 expression in human samples.CD107a/LAMP-1 is a critical marker associated with lysosomal function and membrane trafficking, playing key roles in cellular processes such as antigen presentation, lysosomal exocytosis, and immune responses. The H4A3 antibody, optimized for human tissue samples, enables precise visualization and quantification of CD107a/LAMP-1 expression, making it an invaluable tool for investigating lysosomal biology, immunology, and related research areas.

With its superior performance and reliability, the GenieFluor 488 Anti-Human CD107a (LAMP-1) Antibody (H4A3) from AssayGenie is ideal for scientists and researchers seeking to delve deeper into the mechanisms underlying vesicular trafficking, immune cell activation, and intracellular protein degradation processes. Unleash the power of high-quality antibody technology with AssayGenie's innovative product for your next groundbreaking research project.

Product Title:GenieFluor 488 Anti-Human CD107a/LAMP-1 Antibody [H4A3]
SKU:AGEL3150
Size:20 Tests, 100 Tests, 200 Tests
Clone No:H4A3
Synonyms:Lysosome-Associated Membrane Protein 1; LGP-120; LAMP-1;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Genie Fluor 488 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P11279
Gene ID:3916
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD107a, also known as Lysosome-Associated Membrane Protein 1 (LAMP-1) or LGP-120, is a 110-140 kD type I membrane glycoprotein. Mature CD107a is heavily glycosylated from a 40 kD core protein. This molecule is located on the luminal side of lysosomes. Upon activation, CD107a is transferred to the cell membrane surface of activated platelets, activated lymphocytes, macrophages, epithelial cells, endothelial cells, and some tumor cells. CD107a has been suggested to play a role in the protection of lysosomal membrane from lysosomal hydrolases which is involved in cell adhesion and regulation of tumor metastasis, and mediates autoimmune disease progression. CD107a is a ligand for galaptin and E-selectin. Surface expression of LAMP-1 has been shown to correlate with CD8+ T cell and NK cell cytotoxicity.

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