GMNN Rabbit Polyclonal Antibody (CAB5316)
- SKU:
- CAB5316
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | GMNN Rabbit Polyclonal Antibody |
SKU: | CAB5316 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-209 of human GMNN (NP_056979.1). |
Sequence: | MNPS MKQK QEEI KENI KNSS VPRR TLKM IQPS ASGS LVGR ENEL SAGL SKRK HRND HLTS TTSS PGVI VPES SENK NLGG VTQE SFDL MIKE NPSS QYWK EVAE KRRK ALYE ALKE NEKL HKEI EQKD NEIA RLKK ENKE LAEV AEHV QYMA ELIE RLNG EPLD NFES LDNQ EFDS EEET VEDS LVED SEIG TCAE GTVS SSTD AKPC I |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | Gem; MGORS6; GMNN |
Positive Sample: | HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 24kDa |
Observed MW: | 30kDa |
This gene encodes a protein that plays a critical role in cell cycle regulation. The encoded protein inhibits DNA replication by binding to DNA replication factor Cdt1, preventing the incorporation of minichromosome maintenance proteins into the pre-replication complex. The encoded protein is expressed during the S and G2 phases of the cell cycle and is degraded by the anaphase-promoting complex during the metaphase-anaphase transition. Increased expression of this gene may play a role in several malignancies including colon, rectal and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and two pseudogenes of this gene are located on the short arm of chromosome 16.
Purification Method: | Affinity purification |
Gene ID: | 51053 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |