GEMIN8 Rabbit Polyclonal Antibody (CAB13708)
- SKU:
- CAB13708
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | GEMIN8 Rabbit Polyclonal Antibody |
SKU: | CAB13708 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-242 of human GEMIN8 (NP_060326.1). |
Sequence: | MAAV KAST SKAT RPWY SHPV YARY WQHY HQAM AWMQ SHHN AYRK AVES CFNL PWYL PSAL LPQS SYDN EAAY PQSF YDHH VAWQ DYPC SSSH FRRS GQHP RYSS RIQA STKE DQAL SKEE EMET ESDA EVEC DLSN MEIT EELR QYFA ETER HREE RRRQ QQLD AERL DSYV NADH DLYC NTRR SVEA PTER PGER RQAE MKRL YGDS AAKI QAME AAVQ LSFD KHCD RKQP KYWP VIPL KF |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | FAM51A1; GEMIN8 |
Positive Sample: | A-549,HT-29,HepG2 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus, gem. |
Calculated MW: | 29kDa |
Observed MW: | 35kDa |
The protein encoded by this gene is part of the SMN complex, which is necessary for spliceosomal snRNP assembly in the cytoplasm and pre-mRNA splicing in the nucleus. The encoded protein binds to both SMN1 and the GEMIN6/GEMIN7 heterodimer, mediating their interaction. This protein is found in nuclear Gemini of Cajal bodies (gems) and in the cytoplasm. Three transcript variants encoding the same protein have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 54960 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |