The Gemin8 Polyclonal Antibody (CAB13708) is a valuable tool for researchers studying Gemin8, a crucial protein involved in RNA processing and transcription regulation. This antibody, developed using rabbits as the host species, exhibits high specificity and sensitivity towards Gemin8 in human samples, making it an ideal choice for Western blot applications.Gemin8 plays a pivotal role in various cellular processes, including mRNA export from the nucleus and the assembly of spliceosomal complex. Dysregulation of Gemin8 has been linked to abnormalities in gene expression and RNA metabolism, highlighting its importance in maintaining normal cellular function.
By utilizing the Gemin8 Polyclonal Antibody, researchers can accurately detect and quantify Gemin8 levels in different cell types, enabling a deeper understanding of its mechanisms of action. This antibody is a valuable tool for studies focusing on RNA biology, gene regulation, and potential therapeutic targets for diseases associated with aberrant RNA processing.Invest in the Gemin8 Polyclonal Antibody (CAB13708) for high-quality results in your research endeavors related to Gemin8 and its role in cellular processes. Unlock the potential of Gemin8 as a key player in RNA metabolism and transcription regulation with this reliable and specific antibody.
Product Name:
GEMIN8 Rabbit Polyclonal Antibody
SKU:
CAB13708
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-242 of human GEMIN8 (NP_060326.1).
The protein encoded by this gene is part of the SMN complex, which is necessary for spliceosomal snRNP assembly in the cytoplasm and pre-mRNA splicing in the nucleus. The encoded protein binds to both SMN1 and the GEMIN6/GEMIN7 heterodimer, mediating their interaction. This protein is found in nuclear Gemini of Cajal bodies (gems) and in the cytoplasm. Three transcript variants encoding the same protein have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
54960
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using GEMIN8 Rabbit pAb (CAB13708) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
