The Gemin6 Polyclonal Antibody (CAB12375) is a highly specific research tool designed for studying Gemin6, a protein involved in pre-mRNA splicing and mRNA export processes. This antibody, generated in rabbits, exhibits strong reactivity towards human samples and has been validated for use in Western blot applications. By binding to the Gemin6 protein, researchers can accurately detect and analyze its expression in various cell types, making it an essential tool for studies in molecular biology and gene expression regulation.Gemin6 is a key player in the spliceosome complex, essential for proper mRNA processing and gene expression. Dysregulation of Gemin6 has been linked to various diseases, including spinal muscular atrophy and other neurodegenerative disorders.
By elucidating the function and regulation of Gemin6, researchers can gain valuable insights into the mechanisms underlying these diseases and potentially identify new therapeutic targets for intervention.The Gemin6 Polyclonal Antibody is a valuable resource for researchers interested in delving deeper into the intricate processes of mRNA splicing and gene expression. Its high specificity, sensitivity, and reliability make it an indispensable tool for advancing our understanding of Gemin6 biology and its implications in health and disease.
Product Name:
GEMIN6 Rabbit Polyclonal Antibody
SKU:
CAB12375
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-167 of human GEMIN6 (NP_079051.9).
GEMIN6 is part of a large macromolecular complex, localized to both the cytoplasm and the nucleus, that plays a role in the cytoplasmic assembly of small nuclear ribonucleoproteins (snRNPs). Other members of this complex include SMN (MIM 600354), GEMIN2 (SIP1; MIM 602595), GEMIN3 (DDX20; MIM 606168), GEMIN4 (MIM 606969), and GEMIN5 (MIM 607005).
Purification Method:
Affinity purification
Gene ID:
79833
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using GEMIN6 Rabbit pAb (CAB12375) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
