Gemin 2 Rabbit Polyclonal Antibody (CAB3082)
- SKU:
- CAB3082
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | Gemin 2 Rabbit Polyclonal Antibody |
SKU: | CAB3082 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 180-280 of human Gemin 2 (NP_003607.1) |
Sequence: | LSIV SRMN QATV TSVL EYLS NWFG ERDF TPEL GRWL YALL ACLE KPLL PEAH SLIR QLAR RCSE VRLL VDSK DDER VPAL NLLI CLVS RYFD QRDL ADEP S |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | SIP1; SIP1-delta; Gemin 2 |
Positive Sample: | Jurkat |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus, gem. |
Calculated MW: | 32kDa |
Observed MW: | 35kDa |
This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration.
Purification Method: | Affinity purification |
Gene ID: | 8487 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |