The Gem Polyclonal Antibody (CAB7433) is a powerful tool for researchers studying the Gem protein, a member of the RGK (Rad, Rem, Rem2, and Gem/Kir) family of small GTPases. This antibody, produced in rabbits, shows high specificity for human samples and is well-suited for use in Western blot applications. By binding to the Gem protein, this antibody allows for precise detection and analysis in a variety of cell types, making it an excellent choice for studies focused on signal transduction pathways and cellular processes.Gem, known for its role in regulating cell growth, differentiation, and apoptosis, is a key player in various cellular functions including neuronal development, cardiovascular function, and cancer progression.
Understanding the mechanisms behind Gem's activity is essential for unraveling its significance in both normal and disease conditions. This antibody provides researchers with a reliable tool for investigating Gem's involvement in various biological processes, making it a valuable asset in studies related to cancer biology, neurobiology, and cardiovascular research.
Product Name:
GEM Rabbit Polyclonal Antibody
SKU:
CAB7433
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human GEM (NP_005252.1).
The protein encoded by this gene belongs to the RAD/GEM family of GTP-binding proteins. It is associated with the inner face of the plasma membrane and could play a role as a regulatory protein in receptor-mediated signal transduction. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.
Purification Method:
Affinity purification
Gene ID:
2669
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GEM antibody (CAB7433) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
