The GDPD5 Polyclonal Antibody (PACO09444) is a valuable tool for researchers studying GDPD5, a phospholipase enzyme involved in lipid metabolism and cell signaling pathways. This antibody is produced in rabbits and exhibits strong reactivity with human samples, making it ideal for use in Western blot applications. By specifically binding to the GDPD5 protein, this antibody enables accurate detection and analysis in a variety of cell types, providing valuable insights for studies in lipid metabolism, signal transduction, and related research areas.GDPD5 plays a crucial role in regulating lipid homeostasis and cellular signaling processes, making it a key target for investigating metabolic disorders, cancer biology, and other diseases associated with dysregulated lipid metabolism.
Understanding the functions and mechanisms of GDPD5 can offer important insights for developing novel therapeutic strategies targeting lipid-related pathways. The validation of this antibody for Western blot applications ensures reliable and reproducible results, making it a valuable asset for researchers interested in exploring the roles of GDPD5 in health and disease.
GDPD5: Promotes neurite formation. Cooperates with PRDX1 to drive postmitotic motor neuron differentiation. The glycerophosphodiester phosphodiesterase activity may be required for its role in neuronal differentiation. May contribute to the osmotic regulation of cellular glycerophosphocholine. Belongs to the glycerophosphoryl diester phosphodiesterase family. 5 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integral; Phosphodiesterase; Membrane protein, multi-pass; EC 3.1.-.-Chromosomal Location of Human Ortholog: 11q13.4-q13.5Molecular Function: protein binding
UniProt Protein Details:
NCBI Summary:
Glycerophosphodiester phosphodiesterases (GDPDs; EC 3.1.4.46), such as GDPD5, are involved in glycerol metabolism (Lang et al., 2008 [PubMed 17578682]).[supplied by OMIM, Jan 2010]