GDF7 Antibody (PACO55986)
- SKU:
- PACO55986
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
GDF7 Antibody (PACO55986)
The GDF7 Antibody (PAC055986) is a critical tool for research involving Growth Differentiation Factor 7 (GDF7), a member of the TGF-beta superfamily of cytokines. This polyclonal antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in a variety of applications, including Western blot and immunohistochemistry.GDF7 is known to play a significant role in various biological processes, including cell growth, differentiation, and development. Its functions in skeletal and cardiovascular development make it a key target for research in areas such as regenerative medicine, musculoskeletal disorders, and cardiovascular diseases.
The GDF7 Antibody enables the detection and analysis of GDF7 protein expression in different cell types, providing valuable insights for researchers studying these processes.By utilizing the GDF7 Antibody in their studies, researchers can gain a better understanding of the mechanisms by which GDF7 contributes to the regulation of key biological processes. This knowledge has the potential to lead to the development of novel therapeutic strategies for conditions related to skeletal and cardiovascular development, as well as potential applications in tissue regeneration and repair.
| Antibody Name: | GDF7 Antibody (PACO55986) |
| Antibody SKU: | PACO55986 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:200-1:500 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Growth/differentiation factor 7 protein (322-450AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: A549 whole cell lysate. All lanes: GDF7 antibody at 7.9µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 47 kDa. Observed band size: 47 kDa. |
 | IHC image of PACO55986 diluted at 1:300 and staining in paraffin-embedded human lung cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
 | IHC image of PACO55986 diluted at 1:300 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| Background: | May play an active role in the motor area of the primate neocortex. |
| Synonyms: | Growth/differentiation factor 7 (GDF-7), GDF7 |
| UniProt Protein Function: | GDF7: May play an active role in the motor area of the primate neocortex. Belongs to the TGF-beta family. |
| UniProt Protein Details: | Protein type:Cytokine; Secreted; Secreted, signal peptide; Cell development/differentiation Chromosomal Location of Human Ortholog: 2p24.1 Cellular Component: extracellular space Molecular Function:cytokine activity; growth factor activity; protein binding; protein homodimerization activity; transforming growth factor beta receptor binding Biological Process: activin receptor signaling pathway; axon guidance; BMP signaling pathway; branching morphogenesis of a tube; cell development; cell fate commitment; epithelial cell differentiation; forebrain morphogenesis; gland morphogenesis; growth; midbrain development; positive regulation of neuron differentiation; positive regulation of transcription, DNA-dependent; regulation of apoptosis; regulation of MAPKKK cascade; reproductive structure development; roof plate formation; spinal cord association neuron differentiation |
| NCBI Summary: | This gene encodes a member of the bone morphogenetic protein (BMP) family. BMPs belong to the transforming growth factor-beta superfamily of secreted signalling molecules that regulate diverse processes in growth, repair and embryonic development. In mouse, this gene functions as an inductive signal from the roof plate required for the specification of neuronal identity in the dorsal spinal cord. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q7Z4P5 |
| NCBI GenInfo Identifier: | 296434517 |
| NCBI Gene ID: | 151449 |
| NCBI Accession: | Q7Z4P5.2 |
| UniProt Related Accession: | Q7Z4P5 |
| Molecular Weight: | 46,950 Da |
| NCBI Full Name: | Growth/differentiation factor 7 |
| NCBI Synonym Full Names: | growth differentiation factor 7 |
| NCBI Official Symbol: | GDF7Â Â |
| NCBI Official Synonym Symbols: | BMP12Â Â |
| NCBI Protein Information: | growth/differentiation factor 7 |
| UniProt Protein Name: | Growth/differentiation factor 7 |
| Protein Family: | Growth/differentiation factor |
| UniProt Gene Name: | GDF7Â Â |
| UniProt Entry Name: | GDF7_HUMAN |
| Antibodies | ELISA Kits |
| GDF7 Antibody (PACO02526) | Human GDF7 ELISA Kit |
| GDF7 Antibody (PACO06927) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
Related Products
GDF7 Antibody (PACO06927)
GDF7 Antibody (PACO02526)
GDF7 Antibody (PACO17981)
GDF7 Antibody (PACO22355)
Mouse GDF7 ELISA Kit
