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GDF7 Antibody (PACO02526)

SKU:
PACO02526
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€269
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Description

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GDF7 Antibody (PACO02526)

The GDF7 Polyclonal Antibody (PACO02526) is an essential tool for research involving GDF7, a member of the bone morphogenetic protein (BMP) family that plays a crucial role in skeletal development and repair. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the GDF7 protein, it enables accurate detection and analysis in a variety of cell types, making it an excellent choice for studies in developmental biology and tissue regeneration.GDF7, also known as growth/differentiation factor 7, is a key regulator of bone and cartilage formation, making it a promising target for research aimed at understanding and treating skeletal disorders such as osteoporosis and osteoarthritis.

Its role in promoting bone growth and repair highlights its potential as a therapeutic agent for regenerative medicine applications. By investigating the function of GDF7, researchers can gain valuable insights into the mechanisms underlying skeletal development and explore new avenues for therapeutic intervention.

Antibody Name:GDF7 Antibody
Antibody SKU:PACO02526
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, WB
Recommended Dilutions:WB:1:500-1:2000
Species Reactivity:Human
Immunogen:synthesized peptide derived from the Internal region of human GDF-7.
Form:Liquid
Storage Buffer:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:GDF7; Growth/differentiation factor 7; GDF-7
UniProt Protein Function:GDF7: May play an active role in the motor area of the primate neocortex. Belongs to the TGF-beta family.
UniProt Protein Details:

Protein type:Cytokine; Secreted; Secreted, signal peptide; Cell development/differentiation

Chromosomal Location of Human Ortholog: 2p24.1

Cellular Component: extracellular space

Molecular Function:cytokine activity; growth factor activity; protein binding; protein homodimerization activity; transforming growth factor beta receptor binding

Biological Process: activin receptor signaling pathway; axon guidance; BMP signaling pathway; branching morphogenesis of a tube; cell development; cell fate commitment; epithelial cell differentiation; forebrain morphogenesis; gland morphogenesis; growth; midbrain development; positive regulation of neuron differentiation; positive regulation of transcription, DNA-dependent; regulation of apoptosis; regulation of MAPKKK cascade; reproductive structure development; roof plate formation; spinal cord association neuron differentiation

NCBI Summary:This gene encodes a member of the bone morphogenetic protein (BMP) family. BMPs belong to the transforming growth factor-beta superfamily of secreted signalling molecules that regulate diverse processes in growth, repair and embryonic development. In mouse, this gene functions as an inductive signal from the roof plate required for the specification of neuronal identity in the dorsal spinal cord. [provided by RefSeq, Jul 2008]
UniProt Code:Q7Z4P5
NCBI GenInfo Identifier:296434517
NCBI Gene ID:151449
NCBI Accession:Q7Z4P5.2
UniProt Related Accession:Q7Z4P5
Molecular Weight:46,950 Da
NCBI Full Name:Growth/differentiation factor 7
NCBI Synonym Full Names:growth differentiation factor 7
NCBI Official Symbol:GDF7  
NCBI Official Synonym Symbols:BMP12  
NCBI Protein Information:growth/differentiation factor 7
UniProt Protein Name:Growth/differentiation factor 7
Protein Family:Growth/differentiation factor
UniProt Gene Name:GDF7  
UniProt Entry Name:GDF7_HUMAN

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