GDF15 Monoclonal Antibody (CAB22097)
- SKU:
- CAB22097
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
Product Name: | GDF15 Monoclonal Antibody |
SKU: | CAB22097 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human GDF15 (NP_004855.2). |
Sequence: | HLHL RISR AALP EGLP EASR LHRA LFRL SPTA SRSW DVTR PLRR QLSL ARPQ APAL HLRL SPPP SQSD QLLA ESSS ARPQ LELH LRPQ AARG RRRA RARN G |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 |
Synonyms: | PDF; MIC1; PLAB; MIC-1; NAG-1; PTGFB; GDF-15; GDF15 |
Positive Sample: | HT-1080+PMA/TPA |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 34kDa |
Observed MW: | 15kDa/35kDa |
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The protein is expressed in a broad range of cell types, acts as a pleiotropic cytokine and is involved in the stress response program of cells after cellular injury. Increased protein levels are associated with disease states such as tissue hypoxia, inflammation, acute injury and oxidative stress.
Purification Method: | Affinity purification |
Gene ID: | 9518 |
Clone Number: | ARC55565 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |