The GDF-8/Myostatin Monoclonal Antibody is a cutting-edge tool for researchers studying myostatin, a key regulator of skeletal muscle growth and development. This antibody, produced in a monoclonal format, is highly specific for detecting and quantifying GDF-8/Myostatin protein levels in various samples, including cell lysates and tissues.Myostatin is known for its role in controlling muscle mass, making it a crucial target for studies focused on muscle physiology, exercise science, and muscle wasting conditions like muscular dystrophy. This monoclonal antibody allows for precise measurement and analysis of myostatin levels, enabling researchers to deepen their understanding of the pathways and mechanisms involved in muscle regulation.
With its high specificity and sensitivity, the GDF-8/Myostatin Monoclonal Antibody is a valuable tool for researchers seeking to uncover new insights into muscle biology and develop potential therapeutic strategies for muscle-related disorders. Its reliability and performance make it a trusted choice for studies exploring the diverse functions of myostatin in health and disease.
Product Name:
GDF-8/Myostatin Monoclonal Antibody
SKU:
CAB22725
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 24-375 of human GDF-8/Myostatin(NP_005250.1).
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals.
Purification Method:
Affinity purification
Gene ID:
2660
Clone Number:
ARC57469
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using GDF-8/Myostatin Rabbit mAb (CAB22725) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
