The GDAP2 Polyclonal Antibody (PAC040902) is a valuable tool for researchers studying GDAP2, a protein associated with Charcot-Marie-Tooth disease. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By targeting the GDAP2 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it an essential tool for studies in neurology and genetic disorders.GDAP2 is a key player in the maintenance of peripheral nerve function and mutations in this gene have been linked to the development of Charcot-Marie-Tooth disease, a hereditary neuropathy.
Understanding the role of GDAP2 in nerve function is crucial for advancing research into therapies for this debilitating condition. By targeting GDAP2 with this antibody, researchers can gain valuable insights into the mechanisms underlying Charcot-Marie-Tooth disease and potentially identify new treatment approaches.
Antibody Name:
GDAP2 Antibody (PACO40902)
Antibody SKU:
PACO40902
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:2000
Species Reactivity:
Human
Immunogen:
Recombinant Human Ganglioside-induced differentiation-associated protein 2 protein (1-496AA)
Western blot. All lanes: GDAP2 antibody at 2µg/ml + MCF-7 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 57 kDa. Observed band size: 57 kDa.
Synonyms:
Ganglioside-induced differentiation-associated protein 2, GDAP2
UniProt Protein Function:
GDAP2: Belongs to the GDAP2 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 1p12Cellular Component: lysosomal membraneMolecular Function: protein bindingBiological Process: response to retinoic acid
