GDAP1L1 Antibody (PACO26933)
- SKU:
- PACO26933
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
GDAP1L1 Antibody (PACO26933)
The GDAP1L1 polyclonal antibody (PAC026933) is a valuable tool for researchers studying GDAP1L1, a protein involved in mitochondrial dynamics and peripheral neuropathies. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in various research applications, including immunofluorescence and immunohistochemistry.GDAP1L1 is a key player in maintaining mitochondrial morphology and function, making it a crucial focus in the study of neurodegenerative diseases and metabolic disorders.
Dysregulation of GDAP1L1 has been linked to peripheral neuropathies, highlighting its potential as a therapeutic target in the development of treatments for these conditions.By specifically detecting GDAP1L1 protein expression, this polyclonal antibody enables researchers to investigate its role in mitochondrial dynamics and disease pathology. Its versatility and specificity make it an essential tool for advancing our understanding of GDAP1L1 function and its implications in human health.
| Antibody Name: | GDAP1L1 Antibody (PACO26933) |
| Antibody SKU: | PACO26933 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Ganglioside-induced differentiation-associated protein 1-like 1 protein (101-260AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: GDAP1L1 antibody at 8µg/ml + Hela whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 42, 17, 44 kDa Observed band size: 42 kDa . |
 | Immunohistochemistry of paraffin-embedded human pancreatic tissue using PACO26933 at dilution of 1:100. |
| Background: | cytoplasm, glutathione transferase activity, glutathione metabolic process |
| Synonyms: | Ganglioside-induced differentiation-associated protein 1-like 1 (GDAP1-L1), GDAP1L1 |
| UniProt Protein Function: | GDAP1L1: The ganglioside GD3 synthase causes cell differentiation with neurite sprouting when transfected into the mouse neuroblastoma cell line Neuro2a. After differentiation, the expression of several genes is upregulated, including one that encodes a protein termed ganglioside-induced differentiation-associated protein 1 (Gdap1). A similar gene was found in humans, and mutations in the human gene are associated with Charcot-Marie-Tooth type 4A disease. The protein encoded by this gene is similar in sequence to the human GDAP1 protein. Several transcript variants encoding different isoforms, as well as a noncoding transcript variant, have been found for this gene. [provided by RefSeq, Feb 2012]Chromosomal Location of Human Ortholog: 20q12 |
| UniProt Protein Details: | |
| NCBI Summary: | The ganglioside GD3 synthase causes cell differentiation with neurite sprouting when transfected into the mouse neuroblastoma cell line Neuro2a. After differentiation, the expression of several genes is upregulated, including one that encodes a protein termed ganglioside-induced differentiation-associated protein 1 (Gdap1). A similar gene was found in humans, and mutations in the human gene are associated with Charcot-Marie-Tooth type 4A disease. The protein encoded by this gene is similar in sequence to the human GDAP1 protein. Several transcript variants encoding different isoforms, as well as a noncoding transcript variant, have been found for this gene. [provided by RefSeq, Feb 2012] |
| UniProt Code: | Q96MZ0 |
| NCBI GenInfo Identifier: | 38257738 |
| NCBI Gene ID: | 78997 |
| NCBI Accession: | Q96MZ0.2 |
| UniProt Secondary Accession: | Q96MZ0,Q5TE60, Q68CW7, Q9BQJ7, Q9BQV4, Q9BWJ4, Q9H3Y2 Q9H4G5, B7Z621 |
| UniProt Related Accession: | Q96MZ0 |
| Molecular Weight: | |
| NCBI Full Name: | Ganglioside-induced differentiation-associated protein 1-like 1 |
| NCBI Synonym Full Names: | ganglioside induced differentiation associated protein 1-like 1 |
| NCBI Official Symbol: | GDAP1L1Â Â |
| NCBI Official Synonym Symbols: | dJ881L22.1; dJ995J12.1.1Â Â |
| NCBI Protein Information: | ganglioside-induced differentiation-associated protein 1-like 1; GDAP1-L1 |
| UniProt Protein Name: | Ganglioside-induced differentiation-associated protein 1-like 1 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Ganglioside-induced differentiation-associated protein |
| UniProt Gene Name: | GDAP1L1Â Â |
| UniProt Entry Name: | GD1L1_HUMAN |
| Antibodies |
| GDAP1L1 Antibody (PACO09440) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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GDAP1L1 Antibody (PACO09440)
