The GDAP1 Polyclonal Antibody (CAB6601) is a valuable tool for researchers studying GDAP1, a protein involved in peripheral nervous system function and implicated in Charcot-Marie-Tooth disease. This antibody, generated in rabbits, shows high reactivity with human samples and is validated for use in Western blot applications.GDAP1, or ganglioside-induced differentiation-associated protein 1, is important for maintaining mitochondrial function and proper nerve cell development. Mutations in the GDAP1 gene can lead to neurological disorders like CMT, a group of inherited neuropathies.
By detecting GDAP1 levels in various cell types, this antibody aids in understanding its role in neurodegenerative diseases and potential therapeutic strategies.Researchers studying mitochondrial dysfunction, peripheral neuropathies, and genetic disorders will benefit from using the GDAP1 Polyclonal Antibody. Its specificity and reliability make it a valuable tool for exploring the mechanisms underlying these conditions and developing targeted interventions for improved patient outcomes.
Product Name:
GDAP1 Rabbit Polyclonal Antibody
SKU:
CAB6601
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-225 of human GDAP1 (NP_001035808.1).
This gene encodes a member of the ganglioside-induced differentiation-associated protein family, which may play a role in a signal transduction pathway during neuronal development. Mutations in this gene have been associated with various forms of Charcot-Marie-Tooth Disease and neuropathy. Two transcript variants encoding different isoforms and a noncoding variant have been identified for this gene.
Purification Method:
Affinity purification
Gene ID:
54332
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using GDAP1 Rabbit pAb (CAB6601) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
