The GCNA Polyclonal Antibody (PAC060240) is a valuable tool for researchers studying germ cell-specific genes and their role in reproduction and development. This antibody, produced in rabbits, is highly specific to GCNA and has been validated for use in various applications, including Western blotting and immunohistochemistry.GCNA, or germ cell nuclear antigen, is a protein that plays a crucial role in the regulation of germ cell development and maintenance. It is primarily expressed in germ cells and is essential for processes such as spermatogenesis and oogenesis.
Aberrant expression of GCNA has been linked to infertility and other reproductive disorders, making it a promising target for further investigation.By using the GCNA Polyclonal Antibody, researchers can effectively detect and analyze GCNA protein levels in different cell types and tissues, providing valuable insights into its function and potential implications in reproductive biology. This antibody is a valuable tool for scientists working in fields such as reproductive medicine, developmental biology, and infertility research.
Western Blot. Positive WB detected in: HepG2 whole cell lysate, A549 whole cell lysate. All lanes: GCNA antibody at 4.3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 77 kDa. Observed band size: 77 kDa.
IHC image of PACO60240 diluted at 1:300 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Background:
nucleus, DNA demethylation
Synonyms:
acid, c repeat-containing protein (Germ cell nuclear antigen), GCNA, ACRC
UniProt Protein Function:
ACRC: Belongs to the serine-aspartate repeat-containing protein (SDr) family.Protein type: Unknown functionChromosomal Location of Human Ortholog: Xq13.1
