The GCN1L1 Polyclonal Antibody (CAB13075) is a valuable tool for researchers studying GCN1L1, a crucial regulator of protein synthesis and cellular stress response. This antibody, raised in rabbits, is highly specific and reactive with human samples, making it ideal for Western blot applications.GCN1L1 is known to play a significant role in the integrated stress response pathway, helping cells adapt to various stressors like nutrient deprivation and viral infections.
Dysregulation of GCN1L1 has been implicated in various diseases, including cancer and neurodegenerative disorders.By specifically targeting the GCN1L1 protein, this polyclonal antibody enables researchers to detect and analyze its expression in different cell types, providing valuable insights into its function and potential therapeutic implications. Its versatility and reliability make it a valuable tool for studies in cell biology, cancer research, and beyond.
Product Name:
GCN1L1 Rabbit Polyclonal Antibody
SKU:
CAB13075
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 2462-2671 of human GCN1L1 (NP_006827.1).
Enables RNA binding activity and cadherin binding activity. Predicted to be involved in cellular response to leucine starvation and positive regulation of transcription from RNA polymerase II promoter in response to stress. Located in cytosol.
Purification Method:
Affinity purification
Gene ID:
10985
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type(WT) and GCN1L1 knockout (KO) 293T(KO) cells, using [KO Validated] GCN1L1 Rabbit pAb (CAB13075) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
