The GCM1 Polyclonal Antibody (CAB7282) is specifically designed for research involving GCM1, a transcription factor essential for placental development and hormone production. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in immunohistochemistry (IHC) and western blot applications. By binding to the GCM1 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an excellent tool for studying placental biology, endocrine disorders, and reproductive health.
GCM1, also known as Glial Cells Missing Homolog 1, is crucial for the differentiation and function of syncytiotrophoblast cells in the placenta, as well as for the production of hormones like parathyroid hormone. Research into GCM1 is vital for understanding placental development, hormone regulation, and reproductive health. This antibody allows for the investigation of GCM1 expression and activity in various biological contexts, providing valuable insights into its role in health and disease.
Product Name:
GCM1 Rabbit Polyclonal Antibody
SKU:
CAB7282
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 207-436 of human GCM1 (NP_003634.2).
This gene encodes a DNA-binding protein with a gcm-motif (glial cell missing motif). The encoded protein is a homolog of the Drosophila glial cells missing gene (gcm). This protein binds to the GCM-motif (A/G)CCCGCAT, a novel sequence among known targets of DNA-binding proteins. The N-terminal DNA-binding domain confers the unique DNA-binding activity of this protein.
Purification Method:
Affinity purification
Gene ID:
8521
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunofluorescence analysis of MCF-7 cells using GCM1 antibody (CAB7282). Blue: DAPI for nuclear staining.
