GCLM Rabbit Monoclonal Antibody (CAB11444)
- SKU:
- CAB11444
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | GCLM Rabbit Monoclonal Antibody |
SKU: | CAB11444 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 175-274 of human GCLM (P48507). |
Sequence: | LYQW AQVK PNSN QVNL ASCC VMPP DLTA FAKQ FDIQ LLTH NDPK ELLS EASF QEAL QESI PDIQ AHEW VPLW LLRY SVIV KSRG IIKS KGYI LQAK RRGS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | GLCLR; GCLM |
Positive Sample: | U-2OS,HeLa,A-431 |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol |
Calculated MW: | 31kDa |
Observed MW: | 30kDa |
Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 2730 |
Clone Number: | ARC0597 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |