GCLM Rabbit Polyclonal Antibody (CAB13989)
- SKU:
- CAB13989
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | GCLM Rabbit Polyclonal Antibody |
SKU: | CAB13989 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-274 of human GCLM (NP_002052.1). |
Sequence: | MGTD SRAA KALL ARAR TLHL QTGN LLNW GRLR KKCP STHS EELH DCIQ KTLN EWSS QINP DLVR EFPD VLEC TVSH AVEK INPD EREE MKVS AKLF IVES NSSS STRS AVDM ACSV LGVA QLDS VIIA SPPI EDGV NLSL EHLQ PYWE ELEN LVQS KKIV AIGT SDLD KTQL EQLY QWAQ VKPN SNQV NLAS CCVM PPDL TAFA KQFD IQLL THND PKEL LSEA SFQE ALQE SIPD IQAH EWVP LWLL RYSV IVKS RGII KSKG YILQ AKRR GS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | GLCLR; GCLM |
Positive Sample: | H460,HT-29,K562,ES2,U-937,22Rv1,U-251MG,mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol, glutamate-cysteine ligase complex |
Calculated MW: | 31kDa |
Observed MW: | 31kDa |
Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 2730 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |