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GCLM Monoclonal Antibody [P2D12AT] (CPAB0119)

SKU:
CPAB0119
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
P2D12AT
€149
Frequently bought together:

Description

system_update_alt Datasheet

GCLM Monoclonal Antibody [P2D12AT] (CPAB0119)

Similarly, the GCLM Polyclonal Antibody (CPAB0119) is a valuable tool for researchers studying the glutamate-cysteine ligase modifier subunit (GCLM) protein. This antibody, also raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By targeting the GCLM protein, researchers can effectively analyze and detect this important enzyme involved in the synthesis of glutathione, an essential antioxidant in the body.GCLM is a key regulatory enzyme in the synthesis of glutathione, which plays a crucial role in protecting cells from oxidative stress and maintaining redox balance. Dysregulation of GCLM expression has been linked to various diseases, including cancer, neurodegenerative disorders, and inflammatory conditions.

The GCLM Polyclonal Antibody provides researchers with the means to investigate the role of GCLM in these diseases and explore potential therapeutic strategies aimed at modulating glutathione levels.In conclusion, the GCLM Polyclonal Antibody is a valuable tool for researchers interested in studying the role of GCLM in health and disease. Its high reactivity and specificity make it an ideal choice for Western blot applications and furthering our understanding of the importance of glutathione metabolism in various physiological and pathological processes.

Product Name:GCLM Antibody
Product Sku:CPAB0119
Size:5μg
Host Species:Mouse
Immunogen:Anti-human GCLM mAb is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human GCLM amino acids 1-274 purified from Ecoli.
Clone:P2D12AT.
Reactivity:Human
Applications:
Purification Method:GCLM antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG1
Background:Glutamate-cysteine ligase (GCLM) is the first rate limiting enzyme of glutathione synthesis. The GCLM enzyme is comprised of 2 subunits, a heavy catalytic subunit and a light regulatory subunit. GCLM deficiency is associated with some forms of hemolytic anemia.
Synonyms:Glutamate--cysteine ligase regulatory subunit, GCS light chain, Gamma-ECS regulatory subunit, Gamma-glutamylcysteine synthetase regulatory subunit, Glutamate--cysteine ligase modifier subunit, GCLM, GLCLR.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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