GCKR Rabbit Polyclonal Antibody (CAB5678)
- SKU:
- CAB5678
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | GCKR Rabbit Polyclonal Antibody |
SKU: | CAB5678 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human GCKR (NP_001477.2). |
Sequence: | MPGT KRFQ HVIE TPEP GKWE LSGY EAAV PITE KSNP LTQD LDKA DAEN IVRL LGQC DAEI FQEE GQAL STYQ RLYS ESIL TTMV QVAG KVQE VLKE PDGG LVVL SGGG TSGR MAFL MSVS FNQL MKGL GQKP LYTY LIAG GDRS VVAS REGT EDSA LHGI EELK KVAA GKKR VIVI GISV GLSA PFVA GQMD CCMN NTAV FLPV LVGF NPVS MARN DPIE DWSS TFRQ VAER MQKM QEKQ KAFV LNPA IGPE GLSG SSRM KGGS ATKI LLET LLLA AHKT VDQG IAAS QRCL LEIL RTFE |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | GKRP; FGQTL5; GCKR |
Positive Sample: | HL-60,Mouse liver,Rat liver,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 69kDa |
Observed MW: | 60-69kDa/69kDa |
This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).
Purification Method: | Affinity purification |
Gene ID: | 2646 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |